eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| primary effusion lymphoma | ||||
| Disease ID | 1198 |
|---|---|
| Disease | primary effusion lymphoma |
| Definition | A rare neoplasm of large B-cells usually presenting as serious effusions without detectable tumor masses. The most common sites of involvement are the pleural, pericardial, and peritoneal cavities. It is associated with HUMAN HERPESVIRUS 8, most often occurring in the setting of immunodeficiency. |
| Synonym | body cavity-based lymphoma effusion lymphoma, primary effusion lymphomas, primary lymphoma, primary effusion lymphoma, primary effusion [disease/finding] lymphomas, primary effusion primary effusion lymphoma (disorder) primary effusion lymphoma (morphologic abnormality) primary effusion lymphomas |
| Orphanet | |
| UMLS | C1292753 |
| MeSH | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:12) C1261473 | sarcoma | 2 C0019158 | hepatitis | 1 C0276535 | aids-related kaposi's sarcoma | 1 C0021390 | inflammatory bowel disease | 1 C0022679 | cystic kidney | 1 C0021831 | bowel disease | 1 C0022658 | kidney disease | 1 C0019163 | hepatitis b | 1 C0036220 | kaposi sarcoma | 1 C0036220 | kaposi's sarcoma | 1 C0031154 | peritonitis | 1 C0007129 | merkel cell carcinoma | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1198 |
|---|---|
| Disease | primary effusion lymphoma |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:8) HP:0003270 | Abdominal distention HP:0002094 | Dyspnea HP:0002202 | Pleural effusion HP:0002721 | Immunodeficiency HP:0012191 | B-cell lymphoma HP:0002027 | Abdominal pain HP:0002585 | Abnormality of the peritoneum HP:0001698 | Pericardial effusion |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:5) HP:0100242 | Sarcoma | 2 HP:0012115 | Liver inflammation | 1 HP:0100726 | Kaposi's sarcoma | 1 HP:0000113 | Polycystic kidney dysplasia | 1 HP:0002586 | Peritonitis | 1 |
| Disease ID | 1198 |
|---|---|
| Disease | primary effusion lymphoma |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:2) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:2) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0002585 | Abnormality of the peritoneum | MP:0004500 | increased incidence of tumors by ionizing radiation induction | higher than normal frequency of tumor incidence induced by radiation in which the individual particle or photon carries sufficient energy to completely remove an electron from its orbit; common types of this radiation include gamma-rays and X-rays |
| HP:0012191 | B-cell lymphoma | MP:0009317 | increased follicular lymphoma incidence | higher than normal incidence of malignant lymphoma arising from lymphoid follicular B cells which may be small or large |
Mapped by homologous gene(Total Items:8) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001698 | Pericardial effusion | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| HP:0002094 | Dyspnea | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0002721 | Immunodeficiency | MP:0020316 | decreased vascular endothelial cell proliferation | decrease in the expansion rate of any vascular endothelial cell population by cell division |
| HP:0002202 | Pleural effusion | MP:0014233 | bile duct epithelium hyperplasia | |
| HP:0002027 | Abdominal pain | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0003270 | Abdominal distention | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0012191 | B-cell lymphoma | MP:0014082 | decreased small intestinal villus height | decreased height of the tiny hair-like projections which protrude from the inside of the small intestine and contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; usually accompanied by crypt elongation or hy |
| HP:0002585 | Abnormality of the peritoneum | MP:0014126 | increased mammary gland apoptosis | increase in the number of any cells of a mammary gland undergoing programmed cell death |
| Disease ID | 1198 |
|---|---|
| Disease | primary effusion lymphoma |
| Case | (Waiting for update.) |